材料与化学研究所
- 姓名： 董立乐
- 性别： 男
- 职称： 副研究员
- 职务：
- 学历：
- 电话：
- 传真：
- 电子邮件： lldong@gia.cas.cn
- 所属部门：
- 通讯地址：
董立乐，副研究员，师从张洪杰院士，面向人民生命健康，围绕智能无机功能材料在医工交叉领域的临床需求，开展系统性研究工作。入职赣江院以来，以第一作者或通讯作者在Adv. Funct. Mater., Adv. Sci., Chem. Eng. J., Nano Today, 等学术期刊上发表相关学术论文10篇。指导王嘉睿、胡光耀研究生获南京分院伍宜孙冠名奖，胡光耀获中国科学技术大学优秀毕业生。
简 历：
社会任职：
超声响应型乳腺癌肺转移药物，胰腺癌抗间质药物，结直肠癌氧化还原药物，食管癌/口腔癌抑制剂、脑胶质瘤电场疗法等制剂的可控制备及其临床转化研究。
研究方向：
承担科研项目情况：
1.Gao He,Xiafei Yu,Junzhe Yang,Lile Dong*,Jialu Xu,Xian Wu,Xiang Li,Xiaoan Liu*. Piezoelectric-Driven Immunosuppressive Remodeling: Ferroptosis/Macrophage Reprogramming for Tumor Therapy. Chem. Eng. J. 2025,520,165769.
2.Kexin Zhang,Dong Li,Kaiyang Wang,Bingbing Duan,Lichao Zhu,Renmiao Peng,Wenjing Lv,Shunye Zhang,Yiting Ma,Guanwei Cheng,Xijian Liu,Lingxiao Zhang,Xiaofeng Zhu*,Lile Dong*,Yu Luo*. Lattice-distortion and Defect Induced Niobium-based Perovskite Polarization Cascade Regulates Na+/K+ ATPase to Enhance Pyroptosis for Cancer Treatment. Adv. Funct. Mater. 2025,e11949.
3.Renmiao Peng,Gulizhaer Ainiwa,Yu Luo,* Kexin Zhang,Rui Zhang,Bingbing Duan,Xinyu Xiang,Wenjing Lv,Lichao Zhu,Jiarui Wang,Xijian Liu,Zhiguang Fu,* Kaiyang Wang,* and Lile Dong*. Cascade-amplified Oxidative Stress via Bandgap-Tuned KBiO3 Perovskite for Cancer Therapy. Small 2025,21,2501860.
4.Jiarui Wang,Gao He, Lile Dong,* Xujian Yang,Hongpeng You,Shuyan Song*. Nanoconfined heterojunctions with enhanced piezoelectricity for amplifying reactive oxygen species storms-triggered tumor ferroptosis-like/apoptosis. Nano Today 2025,64,102785.
5.Guangyao Hu,Jiarui Wang,Lulu Chen,* Haoqin Zheng,Yuanpei Lan,Kaiyang Wang,Xijian Liu,Hongpeng You,Yu Luo,* and Lile Dong*. Small-Bandgap Transducers Induced Carrier Separation for In Situ Dual-Amplified Tumor Oxidative Stress. Adv. Funct. Mater. 2024,34,2401897.
6.Jiarui Wang,Haoqin Zheng,Guangyao Hu,Xujian Yang,Hongpeng You,Lile Dong,* and Shuyan Song*. Novel Spatially Asymmetric Copper Bismuthate-Mediated Augmentation of Energy Conversion to Realize “Three-Step”Tumor Suppression. Adv. Sci. 2024,11,2402599.
7. Dong Li,Kexin Zhang,Kaiyang Wang,* Renmiao Peng,Xijian Liu,Yamei Miao,Yuanpei Lan,Ruizhi Wang,* Lile Dong,* and Yu Luo*. Sono-blasting Triggered Cascading-amplification of Oxidative Stress for Enhanced Interventional Therapy of Hepatocellular Carcinoma. Nano Lett. 2024,24,8996.
8.Jianhui Wang,Lile Dong,* Zeyu Lyu,Dashuai Sun,Taixing Tan,and Hongpeng You*. Facile Synthesis of Highly Efficient and Thermally Stable BaAl4Sb2O12:Eu2+ Phosphor in Air. Adv. Funct. Mater. 2023,33,2214611.
9.Lile Dong,Wenjuan Li,Yu Luo,* Chaoran Liu,Kai Li,Yu Chen* and Guobin Hong*. Engineering Molybdenum-Assisted Tellurium Nanosonosensitizers for Enhanced Sonodynamic Tumor Nanotherapy. Adv. Funct. Mater. 2023,33,2302541.
10.Meifang Zhang,Lile Dong*,Dong Li,Lichao Zhu,Renmiao Peng,Xijian Liu,Kaiyang Wang,Xia Wang,Yicheng Zhu*,Haitao Sun*,Yu Luo*. Sonocatalytic in situ Induced Oxygen Storm Precision Enhanced Reactive Oxygen Therapy for Pancreatic Cancer. Adv. Funct. Mater. 2023,33,2303451.